I figured I would throw my remembered game into the ring, seeing as it has bothered me for a while now that I can't remember the name of it. In fact, I almost wonder if it existed in some crazy dream of mines.
Basically, it was for the PC and it was educational game that dealt in Math. But it was sort of like a first person shooter. I remember that you were on some type of ship and there were these creatures that you could stun with some type of gun that you had and, on certain doors on the ship, you had to solve a math problem just to unlock it. Also, there were certain rooms that sort of simulated being outside. I don't know. The game was cool though, and I wonder if anyone remembers something like that, even with the small amount of info given.
The only other memory of the game I have is that I think the enemies or something in the game was called Pythagoras. Man, I hope someone remembers this.
Edit: I think the game came out around maybe the late 90s to the early 00s. I remember getting it somewhere around junior high school, so might be 2000.