If your great grand kids try to sell it, maybe. We need to wait for a lot more NES to be in landfills before their value goes up. Power Gloves, and ROB the Robot on the other hand could be worth a few bucks.
Anything that has sold 50+ millions will never be really rare. Well, maybe if you keep a pristine sealed copy until there are only 10 or so left in the world. But a regular, played, yellowing NES that needs a blowjob to get it to work every time... nah.
I think the best thing Nintendo can do for Revolution would have an "iTunes" setup for downloading games onto a HD... you can get like NES games for $5, SNES for $15, N64 for $20... including a Western version of Sin and Punishment, finally Buying the system gives you a $50 coupon to buy whatever games you want off "nTunes" or whatever