Shouta said:
PATLABOR DAMMIT! PATLABOR.
Shouta speaks the truth. I can happily third the Patlabor recommendation and second Maison Ikkoku.
Now, if you really want to get old school:
Space Pirate Captain Harlock - 42 episodes
Galaxy Express 999 - 113 episodes
Yamato - Three TV series of 26, 26 and 25 episodes each
Queen Millennia - 42 episodes
And that's not even counting stuff like Danguard Ace and Starzingers. Matsumoto Reiji, I love you so.
Then there's the wonderful world of sports anime:
Ashita no Joe - Two TV series of 79 and 47 episodes each - BOXING AND DEATH!
Touch - 101 episodes - BASEBALL! TWINS! TRUCKS!
Attack No. 1 - 100 episodes - SHOUJO VOLLEYBALL APOCOLYPSE!
Finally, Ryouko Ikeda represent!
Rose of Versailles - 40 episodes
Oniisama E - 39 episodes
There's also a ton of
World Masterpiece Theatre shows that are good and tend to run for more than 26 episodes. 52 episodes of A Dog of Flanders here, another 52 episodes of 3000 Leagues in Search of Mother there. They're virtually all worth watching.
FnordChan