I don't know about activation but doesn't Virtual PC have decent DX support now? Or is that up and coming?
The game doesn't use shaders or anything but it does use DX 8.1 so I dunno.
I don't have VPC so i can't test it on my mac.
Anyway, haven't gotten much further than whats in the demo (infernal work!).
It's a little rough around the edges here and there, but nothing totally game breaking and considering the price, nothign you wouldn't expect.
The conversation system looks like it could get really interesting later on and I was already having fun with it (you can talk to multiple people at once and go back and forth, which changes their perspective conversation trees).
Other than that, its good ole' fashioned point and click.
There's definitely a lot of potential here, I think once they get some more money and a few more episodes under their belt, the polish will be there.