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http://www.genengnews.com/gen-news-highlights/crispr-eliminates-hiv-in-live-animals/81254287

Due to their innate nature to hide away and remain latent for extended periods of time, HIV infections have proven notoriously difficult to eliminate. Yet now, new data released from a research team led by investigators at the Lewis Katz School of Medicine at Temple University (LKSOM) and the University of Pittsburgh shows that HIV DNA can be excised from the genomes of living animals to eliminate further infection. Additionally, the researchers are the first to perform this feat in three different animal models, including a "humanized" model in which mice were transplanted with human immune cells and infected with the virus. Findings from the new study were published recently in Molecular Therapy in an article entitled “In Vivo Excision of HIV-1 Provirus by saCas9 and Multiplex Single-Guide RNAs in Animal Models.”

This is the first study to demonstrate that HIV-1 replication can be completely shut down and the virus eliminated from infected cells in animals with a powerful gene-editing technology known as CRISPR/Cas9.

 

[Derwind]

I hope this leads to a cure. This is great news.

 

[jchap]

Neat. Next fix cancer plz.

 

[Za-Neen-Jya]

Now just eliminate HPV and herpes and we can all fuck each other raw.

 

[TheMan]

Sounds good, looking forward to never hearing about this again.

 

[QisTopTier]

Fuck yeah, best reverse engineering science has done yet

 

[demosthenes]

Now just eliminate HPV and herpes and we can all fuck each other raw.

Forgetting about the untreatable ghonorea?

 

[Switch Back 9]

Forgetting about the untreatable ghonorea?

And babies, the ultimate STI.

 

[Earthbound64]

Sounds good, looking forward to never hearing about this again.

Truth

 

[HStallion]

And babies, the ultimate STI.

As far as problems go those are pretty easy to get rid of.

 

[l2ounD]

still waiting for my crispr stock to go up

 

[DJwest]

And babies, the ultimate STI.

Lmao

 

[Ahasverus]

Getting there.

 

[OceanBlue]

Every time I hear about CRISPR the news is amazing. What a time to be living in.

 

[metalslimer]

Has CRISPR even been used yet in an actual human trial?

 

[HStallion]

Has CRISPR even been used yet in an actual human trial?

Sure it will be tested on poor people so rich people can live till 300 with no health issues.

 

[Vestal]

 

[Septimus Prime]

the ultimate STI.

 

[RedHill]

This is fantastic news! Medical science is amazing.

 

[pswii60]

Now just eliminate HPV and herpes and we can all fuck each other raw.

I think I'd rather have HIV than herpes. I'd rather have a lot of things than herpes. The Google image search scarred me for life.

 

[Trouble]

Lookin' forward to the planet-wide orgy.

 

[SRG01]

Excellent news. I wonder how CRISPR manages to target dormant HIV-infected cells. Does this technique target all cells instead of targetting only those that present HIV antigens?

Sorry, the STI isn't that great :/

 

[Ray Wonder]

And babies, the ultimate STI.

I had a close call with a life threatening version of this. Can attest.

 

[akira28]

Sure it will be tested on poor people so rich people can live till 300 with no health issues.

if that hasn't already happened in some out of the way European clinic, I'll eat my hat.

 

[Trouble]

Subaru continues a long, storied legacy of ruining perfectly fine cars with stupid looking spoilers.

 

[titiklabingapat]

This is great news. HIV actually inserts itself to the hosts' DNA in some dormant immune cells that live for decades, it's why it so hard to get rid of.

 

[Pandaman]

I think I'd rather have HIV than herpes. I'd rather have a lot of things than herpes. The Google image search scarred me for life.

What. Not only is herpes usually harmless, statistically speaking you probably already have herpes.

 

[BigDes]

I think I'd rather have HIV than herpes. I'd rather have a lot of things than herpes. The Google image search scarred me for life.

Got bad news for you.

 

[Lastgengamer]

This is great news, HIV can suck it.

 

[Harmen]

Great news, this is promising.

Neat. Next fix cancer plz.

Not to be a downer, but cancer is a large group of many diseases.

 

[JaggedSac]

Just listened to CRISP bit on radio Lab this weekend. Cool stuff.

 

[Damerman]

Now just eliminate HPV and herpes and we can all fuck each other raw.

Thiiiiiiiis

 

[Septimus Prime]

Subaru continues a long, storied legacy of ruining perfectly fine cars with stupid looking spoilers.

The added downforce allows the car to cut corners as cleanly as CRISPR cuts DNA.

 

[Noobcraft]

I actually suggested a similar method of treating HIV to some of my old lab partners a couple years ago (in cancer research so it was beyond the scope of our lab). I'll have to shoot them an email. It's cool that someone actually worked through it all.

 

[l2ounD]

Just listened to CRISP bit on radio Lab this weekend. Cool stuff.

Very cool
Link to show;
http://www.radiolab.org/story/update-crispr/

 

[Kthulhu]

What. Not only is herpes usually harmless, statistically speaking you probably already have herpes.

This. If you include oral herpes, like 90% of the world has some form of herpes.

 

[AuthenticM]

Now just eliminate HPV and herpes and we can all fuck each other raw.

Yup

the future is now

 

[MrOogieBoogie]

I think I'd rather have HIV than herpes. I'd rather have a lot of things than herpes. The Google image search scarred me for life.

...

You probably already have herpes? Like 80% of people are asymptomatic to both kinds.

Anyway, is this the weekly HIV cure article or should we be more excited?

 

[JaggedSac]

...

You probably already have herpes? Like 80% of people are asymptomatic to both kinds.

Anyway, is this the weekly HIV cure article or should we be more excited?

CRISPR is crazy shit, be excited.

 

[SolarPowered]

Can't wait for the future. Just gotta hope we don't nuke ourselves to oblivion first.

 

[AuthenticM]

...

You probably already have herpes? Like 80% of people are asymptomatic to both kinds.

Anyway, is this the weekly HIV cure article or should we be more excited?

CRISPR is the real deal. Be very excited.

 

[Lautaro]

I think I'd rather have HIV than herpes. I'd rather have a lot of things than herpes. The Google image search scarred me for life.

No gross images, just information:

https://www.youtube.com/watch?v=aU4VcOQzQm0

 

[MrOogieBoogie]

CRISPR is the real deal. Be very excited.

How the heck haven't I heard of this before now? This technology seems absolutely insane.

 

[Afrikan]

As far as problems go those are pretty easy to get rid of.

 

[Aske]

Amazing news!

This. If you include oral herpes, like 90% of the world has some form of herpes.

The only herpes types that matter in this discussion are the oral/genital sexuality transmitted types, and it's 75%. Sure, most of us have had chicken pox, but that's not going to potentially spread to your partner's junk next time you give them head.

And while 80% of infected people are asymptomatic, there's no way to know for sure; so it doesn't seem smart to throw condoms to the wind and fuck indiscriminately because you assume you'll be free of sores based on probability. Especially not with those odds. An estimated 25% of people are oral and genital herpes free - and 1 in 5 of those people infected will get sores.


http://projectaccept.org/straight-dope-herpes-statistics/

 

[TarNaru33]

Amazing news!



The only herpes types that matter in this discussion are the oral/genital sexuality transmitted types, and it's 75%. Sure, most of us have had chicken pox, but that's not going to potentially spread to your partner's junk next time you give them head.

And while 80% of infected people are asymptomatic, there's no way to know for sure; so it doesn't seem smart to throw condoms to the wind and fuck indiscriminately because you assume you'll be free of sores based on probability. Especially not with those odds. An estimated 25% of people are oral and genital herpes free - and 1 in 5 of those people infected will get sores.


http://projectaccept.org/straight-dope-herpes-statistics/

Why not? If you are part of the 25% that is your loss

Spoiler

j/k

Science usually takes a long ass time to come from animal > human trials > to actual treatment and the way U.S healthcare is, I bet it will be expensive as hell even though everyone should be able to get the cure without cost.

 

[Ultryx]

CRISPR FTW.

 

[Aztechnology]

The future looks a bit brighter.

 

[Fulminator]

Holy moly

Amazing news

 

[Snaku]