I guess since this is posted in OT, gaming doesn't count as big media in the intended sense of the OP. Which is a shame, because gaming was the first media format to really adopt, riff on, and make its own memes. A tri-pronged attack into the heartland of modern memetics.
I guess if we're being stingy, we could say that most gaming memes could be chalked up to referencing other games, or as an in universe reference, but you know. Some count! Surely!
Final Fantasy XII had that Earth elemental Esper (Hashmal, maybe?) whose basic attack was called "roxorz," or whatever, very clearly screamed at a nod to the omfg so quirky uWu MySpace lingo of the time.
Final Fantasy references both Frozen (the cold never bothered me, anyway) and Peter Jackson's LotR (Leiden Potato: Boil it, mash it, or stick it in a stew!)
And I guess this is stretching it, but the English VA's of Metal Gear Solid take every opportunity they can to get in character and absolutely CHEW the scenery. Dummy thiccc, crab battle, omg hotness I wanna bang you, etc, etc
Movies, idfk. Who watches movies, anyway?