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Overclocking your brain with electrical stimulation - BBC article

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Given the option, would you want to think faster and have sharper attention? Research suggests that electrical brain stimulation kits could have just those effects. But now some companies are selling such devices online, leading to calls to regulate the technology.

It may sound too good to be true but scientists say the technology is promising.

Transcranial direct current stimulation (TDCS), which passes small electrical currents directly on to the scalp, stimulates the nerve cells in the brain (neurons).

It's non-invasive, extremely mild and the US military even uses TDCS in an attempt to improve the performance of its drone pilots.
“You need to know how long to stimulate, at what time to stimulate and what intensity to use”


Dr Roy Cohen Kadosh
University of Oxford
The idea is that it makes the neurons more likely to fire and preliminary research suggests electrical simulation can improve attention as well as have a positive impact on people with cognitive impairments and depression.

It has also been shown to increase performance in a maths task, an improvement which was still in place six months later.

The scientist behind this work is Dr Roy Cohen Kadosh from the University of Oxford. He uses TDCS to look at how cognitive functions improve.

He says: "Research has shown that by delivering electricity to the right part of the brain, we can change the threshold of neurons that transmit information in our brain, and by doing that we can improve cognitive abilities in different types of psychological functions."

Studies like his are perhaps why commercial companies are jumping on the technology and largely promoting it as a way to help gamers get ahead.

"A headset for gamers, take charge... Overclock your brain," is how one company promotes it. Another states: "Can you learn 20-40% quicker, reduce pain, feel better, increase energy or reduce stress with tDCS? Research studies say, YES!"

'Unintended results'
But if these devices are used in the wrong way, scientists say they could be harmful.

"If they make claims about gaming, that is very far removed from the sort of treatment claims that might be to do with helping stroke patients or people suffering from depression," warns Hannah Maslen from the Oxford Martin School at Oxford University.

The electrodes of one device seen by the Oxford Martin School (below) are positioned so they stimulate the area of the brain under the forehead.
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This is where the pre-frontal cortex is situated, involved in high-level cognition such as attention.

But in Dr Cohen Kadosh's lab, electrical stimulation is used in a controlled environment for no more than 20 minutes at a time and only on participants who have passed strict medical checks.

Scientists are, after all, applying electrodes to the brain - which they say could have some unintended results.

For example, different brain regions than those intended might be affected and, in some instances, stimulation could impair rather than improve function if the polarity of the stimulation is reversed.

Dr Cohen Kadosh says: "You can use stimulation that might not be beneficial for you, you need to know how long to stimulate, at what time to stimulate and what intensity to use."

Recently, another team of researchers have pleaded for "calm and caution" for these devices when it comes to the developing brain because of the known risks. These can include seizures and mood changes.

Author of this work, Nick Davis from Swansea University, explains that because the brain continues to develop until the age of 20, stimulation in this age group would have a stronger impact.

And more worryingly for him, people are also increasingly making brain stimulation kits themselves. This easily "puts the technology in the realms of clever teenagers," adds Dr Davis.

An active forum on reddit is devoted to the technology, and people there have complained of "burning to the scalp". Another user wrote that they "seemed to be getting angry frequently" after using TDCS.

"These are the people who are probably going to do it at a higher dosage than a scientist or clinician would give to a patient and are less aware of the potential risks," says Dr Davis.

Exploiting hype
These sorts of issues are why a team from the Oxford Martin school at Oxford University is now calling calling for regulation of the commercially sold devices.

Lead author of this paper, Dr Maslen, explains that as they are marketed to gamers and do not make any treatment claims, they avoid the need for regulation.

"If you were to make a treatment claim, that the device would alleviate symptoms or treat a recognised disease or illness, the device would automatically fall under the medical devices directive and the legislation associated with that."

Her team does not want to restrict access to cognitive enhancement devices but wants consumers to have "the information they need to assess what risks they are willing to take in pursuit of which potential benefits".

Another concern is that the science behind these devices is not ready for the commercial market, something Steven Novella a neurologist at Yale University has raised. He says that companies are jumping on the hype of research that is not quite ready for the world because it "sounds very advanced and sexy".

"There's lots of published evidence that could make it seem as if these are proven therapies but I think the marketing is a couple of steps ahead of the science.

"Any device with medical claims that it's meant to affect our biological function should be appropriately regulated. Regulation is the only thing that creates the motivation to spend the money and take the time to do the proper research," he adds.

Suggestions of increased attention and the alleviation of certain medical conditions means interest in electrical stimulation is bound to increase but if the research continues to show promising results it's clear that TDCS will need to be treated with some caution.

http://www.bbc.com/news/health-27343047
Video at link

brb gonna electrocute my prefrontal cortex
 
Really great story over at Radiolab as well: http://www.radiolab.org/story/9-volt-nirvana/

Sally Adee, an editor at New Scientist, was at a conference for DARPA - The Defense Advanced Research Projects Agency - when she heard about a way to speed up learning with something called trans-cranial direct current stimulation (tDCS). A couple years later, Sally found herself weilding an M4 assualt rifle, picking off enemy combatants with a battery wired to her temple. Of course, it was a simulation, but Sally's sniper skills made producer Soren Wheeler wonder what we should think of the world of brain stimulation.​
 

hitme

Member
Really great story over at Radiolab as well: http://www.radiolab.org/story/9-volt-nirvana/

Sally Adee, an editor at New Scientist, was at a conference for DARPA - The Defense Advanced Research Projects Agency - when she heard about a way to speed up learning with something called trans-cranial direct current stimulation (tDCS). A couple years later, Sally found herself weilding an M4 assualt rifle, picking off enemy combatants with a battery wired to her temple. Of course, it was a simulation, but Sally's sniper skills made producer Soren Wheeler wonder what we should think of the world of brain stimulation.​

MGS thread? MGS thread.
 

demon

I don't mean to alarm you but you have dogs on your face
Sounds interesting, I listened to that Radiolab podcast a couple months ago, but I'm worried that years from now I'd start "mysteriously" having seizures or develop a brain tumor or something.
 

TheOMan

Tagged as I see fit
Hard to know how much of this is legitimate and how much of this is typical exaggeration of scientific findings.

I had heard about this years ago, and talked to a neuroscience friend of mine about it. From what he told me, it's definitely legit, freaky, but for real. Hacks for your brain.

Yadayadayada - I'm really really good at math.
 
Hard to know how much of this is legitimate and how much of this is typical exaggeration of scientific findings.

I've fooled around with tDCS, I think a lot of it is exaggeration. Maybe it's helpful in a clinical setting though, idk. A lot of people think it exerts a zero-sum effect though where gains in one area are offset by losses in another, in which case it probably would only be a benefit in cases of psychopathology or whatever.
 
Really great story over at Radiolab as well: http://www.radiolab.org/story/9-volt-nirvana/

Sally Adee, an editor at New Scientist, was at a conference for DARPA - The Defense Advanced Research Projects Agency - when she heard about a way to speed up learning with something called trans-cranial direct current stimulation (tDCS). A couple years later, Sally found herself weilding an M4 assualt rifle, picking off enemy combatants with a battery wired to her temple. Of course, it was a simulation, but Sally's sniper skills made producer Soren Wheeler wonder what we should think of the world of brain stimulation.​

yup, i remember hearing that story and kinda getting interested in making my own machine.

but then i would have no excuse for being so unproductive so i called the whole thing off.
 
Sorry, I'm not changing my #1 rule: don't fuck with your brain.

Give this 50 years of proper research (entirely disconnected from people with the intent to sell stuff), and maybe we'll talk.
 
Sorry, I'm not changing my #1 rule: don't fuck with your brain.

Give this 50 years of proper research (entirely disconnected from people with the intent to sell stuff), and maybe we'll talk.

Literally everything you do fucks with your brain in some way. Even using the internet is effecting your brain. Or reading a book.
 

toxicgonzo

Taxes?! Isn't this the line for Metallica?
It's all fun and games 'til your brain needs a copper heat sink or risks melting into a gray mush liquid.
 
The TDCS reddit is always good for a laugh. Some people in there are relatively responsible (aware of the risks, read the latest research, understand how the technology works), but others are ignorant and foolish. You can electrocute yourself with a 9V battery, so if you don't understand electricity you have no business building your own tDCS unit.
 
The effects of which are well understood or at least better than the long term effects of applying an electrical current to your brain.

Do we fully understand the effects of the internet on the human brain? Really? I'd love to read some of the studies you've read on how it effects things such as language development, or social development.
 
Humans are indeed experts at intuitively knowing what is and isn't healthy. *puts leeches on self to drain excess black bile*



Did anyone in these trials die? I must have missed that.

when the number is larger than just trials and people want more performance from more currents, what do you think will happen.

and just like overclocking also reduces the life of the CPU, i won't be surprised if the life of the brain is shortened as well
 

demon

I don't mean to alarm you but you have dogs on your face
Literally everything you do fucks with your brain in some way. Even using the internet is effecting your brain. Or reading a book.

There's a difference between using a computer and hooking electrodes to your head to shock your brain. The whole thing just sounds too good to be true, and rarely can you break the rule "there's no such thing as a free lunch".
 
The TDCS reddit is always good for a laugh. Some people in there are relatively responsible (aware of the risks, read the latest research, understand how the technology works), but others are ignorant and foolish. You can electrocute yourself with a 9V battery, so if you don't understand electricity you have no business building your own tDCS unit.

this is bad, you should read into nootropics. People can seriously fuck up their brains by taking "smart drugs." I just took astaxanthin (60-90 pills in total) and it seriously fucked up my concentration/focus levels for at least 1 year or more.
 
when the number is larger than just trials and people want more performance from more currents, what do you think will happen.

and just like overclocking also reduces the life of the CPU, i won't be surprised if the life of the brain is shortened as well

You seem to be using the language used in the title of the article as the basis for your argument "they used overclocking so it MUST work like CPUs!" I don't buy it, sorry. I'll wait for actual data instead of maninthemirror's pure speculation based on how computers (which aren't biological) work.

There's a difference between using a computer and hooking electrodes to your head to shock your brain. The whole thing just sounds too good to be true, and rarely can you break the rule "there's no such thing as a free lunch".

There is a difference obviously. My argument is simply that there are a lot of things we do that have unknown effects on the brain. The rule "never fuck with your brain" is kind of dumb in that sense. It would leave you literally unable to do anything.
 

xbhaskarx

Member
Sorry, I'm not changing my #1 rule: don't fuck with your brain.

Give this 50 years of proper research (entirely disconnected from people with the intent to sell stuff), and maybe we'll talk.

I don't need glasses but that's how I feel about Lasik surgery: Let me know how well 80 year olds who had Lasik 50 years ago can see, and then maybe I'd think about it.
 
Meh, I'll stick with the tried and proven nootropics-good old Piracetam and Choline. tDCS does sound interesting but I wonder how much the equipment costs? Doesn't sound like something you'd want to cheap out on. What if it malfunctuons and outputs a much higher voltage than intended?
 
You seem to be using the language used in the title of the article as the basis for your argument "they used overclocking so it MUST work like CPUs!" I don't buy it, sorry. I'll wait for actual data instead of maninthemirror's pure speculation based on how computers (which aren't biological) work.

i am simply saying that when you try to manipulate the brain for a higher performance, it will affect you just like steroids can give you that temporary boost but screw up your health later especially when the brain is a much more sensitive organ than your blood stream
 
this is bad, you should read into nootropics. People can seriously fuck up their brains by taking "smart drugs." I just took astaxanthin (60-90 pills in total) and it seriously fucked up my concentration/focus levels for at least 1 year or more.
Yes, I browse that forum from time to time as well. Like /r/tdcs, it's divided between people who do a lot of research and understand the many risks they're dealing with and people who don't. I don't plan on zapping my brain or ordering any brain pills anytime soon.
 
this is bad, you should read into nootropics. People can seriously fuck up their brains by taking these drugs. I just took astaxanthin and it seriously fucked up my concentration/focus levels for at least 1 year or more.

I think a really gung-ho attitude about these technologies (which is often the attitude you have when you learn about them) can be pretty counterproductive to what your aim is supposed to be. Even in the more benign cases, trying to shift your neurotransmitter levels or whatever in a beneficial direction can just introduce more irregularity. It's interesting too because for most people doing things like optimizing your diet, and sleep hygiene, exercise, and maybe a bit of brain training, or other skill acquisition (bilingualism, etc) would be more beneficial.
 
Really great story over at Radiolab as well: http://www.radiolab.org/story/9-volt-nirvana/

Sally Adee, an editor at New Scientist, was at a conference for DARPA - The Defense Advanced Research Projects Agency - when she heard about a way to speed up learning with something called trans-cranial direct current stimulation (tDCS). A couple years later, Sally found herself weilding an M4 assualt rifle, picking off enemy combatants with a battery wired to her temple. Of course, it was a simulation, but Sally's sniper skills made producer Soren Wheeler wonder what we should think of the world of brain stimulation.​

It's a shame that radiolab shorts don't have transcripts, but some of the cons regarding amateur tDCS should be mentioned:

-Short period of blindness
-Depression
-Anxiousness (after-effect.)

It's not something I would try till more study is available.
 
i am simply saying that when you try to manipulate the brain for a higher performance, it will affect you just like steroids can give you that temporary boost but screw up your health later especially when the brain is a much more sensitive organ than your blood stream

Which is pure speculation on your part. A lot of people are pulling some sort of Full Metal Alchemist type reasoning where they think the universe runs on equivalent exchange. "If it has a good effect it MUST have some terrible horrible potential side effect in the long run."

Which simply isn't true all the time. It isn't some universal law.
 

Cyan

Banned
Funny. The tumor/seizures claim was also leveled at cell phones I believe. And they haven't been around long term either.
Given the mechanisms of seizures, "increase neural activity" seems like a pretty plausible risk factor for seizures.

Literally everything you do fucks with your brain in some way. Even using the internet is effecting your brain. Or reading a book.
Right, but what that poster is presumably getting at is that this direct stimulation feels far more potentially dangerous than such indirect changes.
 

demon

I don't mean to alarm you but you have dogs on your face
this is bad, you should read into nootropics. People can seriously fuck up their brains by taking "smart drugs." I just took astaxanthin (60-90 pills in total) and it seriously fucked up my concentration/focus levels for at least 1 year or more.

A couple years ago I started taking a couple nootropic pills, can't remember which ones but it was a pretty common combination. After a few weeks it made me seriously, deeply depressed. I went off them, tried it again a year later and the same thing happened.

Fuck that shit.

-edit-
Just looked at my amazon order history- it was Piracetam & Inositol/Choline.
 
I think a really gung-ho attitude about these technologies (which is often the attitude you have when you learn about them) can be pretty counterproductive to what your aim is supposed to be. Even in the more benign cases, trying to shift your neurotransmitter levels or whatever in a beneficial direction can just introduce more irregularity. It's interesting too because for most people doing things like optimizing your diet, and sleep hygiene, exercise, and maybe a bit of brain training, or other skill acquisition (bilingualism, etc) would be more beneficial.

This is a really good post. Listen to this man folks! Taking astaxanthin is probably the worst mistake I have ever made, my focus/concentration levels before I took the drug were off the charts. Don't mess with your brain with nootropics or electrical stimulation

A couple years ago I started taking a couple nootropic pills, can't remember which ones but it was a pretty common combination. After a few weeks it made me seriously, deeply depressed. I went off them, tried it again a year later and the same thing happened.

Fuck that shit.

yea, good thing you came off them. I recently tried L-theanine, initially it made me really chill and anxiety free. But when I got a second bottle after finishing the first one, it felt like it was tightening my windpipe, I was having trouble breathing. And the feel good effects of it disappeared. All these drugs, none of them are well studied and it is stupid to experiment with them. I am just gonna stick with a good diet and exercise, which has worked well for me in the past.
 
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