The MC of P5 could just be a girl too ya know. It is not like this series hasn't had experience with female MC's either! Tamaki Uchida of SMT If... (yo its Persona 0 it counts), Maya Amano of Persona 2, Aigis of P3FES, and FemC of P3P.
I'd welcome that too. Though it's pretty unlikely given how many male nerdlingers would be upset that the experience wasn't tailor made for them like P4.