Played:
Mario: Played them all except the Wii games. Not a fan of that controller or waggle to attack. 3D World was fun though.
Yoshi: Played them all except for the DS games. Classics.
Wario: Played most of the Wario Land games, but was never really into WarioWare. It wore out its welcome fast.
Donkey Kong: Haven't touched the Wii/U games. DKC2 is probably the only great one.
Zelda: Twilight Princess and beyond were either boring or bad. Majora's Mask, Wind Waker, and Awakening are my top 3. -EDIT- Forgot about the 3DS one. That's in my top 5.
Pokemon: Haven't played the spinoffs, but LOVED every mainline game. Also, the Mystery Dungeon games are the shit.
Mother: Played Earthbound and Mother 3. Once I finally got the King's Sword naturally, I stopped playing Earthbound. Didn't see how I could do anything else lol.
Metroid: Played Prime once, hated it (I don't care for FPS games). Super Metroid is the GOAT.
Kirby: All great, but each game always disappoints me in a way.
Star Fox: SF64 and Assault are the best games in a poor series, and it makes me sad.

F Zero: Never really touched the SNES one, but 64 and AX/GX are the best. I still have my AX License, too!
Ice Climbers: Played the NES gme once, sisn't like it.
Fire Emblem: I tried Awakening after being convinced it was fun. It was ok, nothing special. No replay value whatsoever, so I traded it in after I was done.
Game and Watch: I owned Game and Watch Gallery on GB when I was younger. I can see why the games never came back.
Kid Icarus: Played the NES game. That was enough for me. =|
Punch Out: Didn't play the Wii one (I never owned or wanted a Wii, there's your answer for the other games as well), but I played the NES and SNES versions to death.
Metal Gear: Played Solid 1, Twin Snakes (the best version), bits of 3, and all of 4. Twin Snakes is my favorite, followed by 4.
Sonic: As President of
SonicGAF, I have played nearly every Sonic game released (aside from Sonic 06, because I'm not a glutton for punishment).
Animal Crossing: Played the GCube one, then stopped after about 3 months. Why play a game about doing chores when I can just do them IRL and actually accomplish something.
Pacman: Obviously I've played Pac-Man. Didn't get to play Championship DX until recently, and it's so good!
Duckhunt: Played a bunch when I was a kid and I was curious about "that other game" on my SMB NES cartridge. Not bad, but boring.
Haven't Played:
Wii Fit: lol fuck dat
Pikmin: Never seemed interesting
ROB: I wasn't a friendless nerd, so my parents saw no need to humiliate me
Miis: I've yet to see a good use for them outside of minigames...well I guess Mario Kart counts?
Xenoblade: Requires a Wii.