As for "feeling uncomfortable" let's face reality here: there are people with a lot of implausible, factually infuckingcorrect views on this earth that people evocate, which produce suffering. The human being is perhaps the most destructive creature on this earth, for this very reason. These people share this world with you and I, and the only way we'd even be close of cleansing the world of this incorrect social conditioning is to confront it. If you leave the ignorant alone, they'll just pair up with more ignorant people and become a vocal minority, becoming a more concentrated bubble of uncomfortability who are bothered by them.
In this case, it need not be trans or even trans supporters who confront a person like Greer, for it can be anyone who can articulate a viewpoint that tries to match the world instead of stamp claims of right and wrong upon it. She is already on incorrect footing for she's evocating an idea onto the world that's not innate to it, regarding "right" women and all of that bunk, and anyone of reason can powerbomb her on those grounds.