Entertainment:
Suzy Lu - mostly gaming, albeit she's been doing anime reactions lately. Mostly her retro gaming, as we have a similar gaming history. Mostly just normal playthroughs of various titles.
The Sphere Hunter - Same as above, sharing a common gaming history and appreciation for certain video game series. Though she takes far more effort in making a script to talk about the game, so it's a far more scripted and focused video experience. More like reviews, analysis, rather than let's play. Also a nice soothing voice.
Mandersnatch - Only started watching recently, as I watched her blind Final Fantasy playthroughs. Really chill.
Girls Play - I don't know what it is, but women acting unabashed and awkward just feels more natural. Just a group of women doing various things like gaming videos and non-gaming videos. Don't fear playing up sex if they want to or being raunchy, but most of all just acts like most women I know.
Jaiden Animations - Pretty big YouTuber, making animation videos about various things about her and her interests. Just really chill to watch.
Various others spazzes that don't fit in a pure "entertainment" category:
Lotus - An Aussie spazz mimicking Filthy Frank initially, but also trying to find her own thing.
Jaclyn Glenn - Doing mostly anti-christian content, which reminds me of my younger self and my own problems with christianity growing up (though Jaclyn is probably a bit too focused on it, imo). She also does videos on other cultural subjects or sometimes music. The reason I watch her is mostly personality though, which makes the videos more fun entertainment when you think about it.
Lana Rain -

Actually a cam girl and cosplay. But what made me subscribe was her great videos on Nier:Automata and her various videos (whether about aspberger's or just showing how geeky she is with her AMV videos). A lot of content is gone now though, as she used to do various promotional videos, whether japanese porn and sex toys, or japanese candy.
Vice also recently did a video about her.
Psych IRL - Does various on topic videos about current events, often analyzing various aspects of them. Really great humor and good production.
Aydin Paladin - Right-wing spazz commentator. Entertaining, even when I disagree with her.