Best games that combine 2D and 3D ?

I dig the idea. Its underutilized in gamedev. Slave zero x is another recent release that tried to tackle this approach:



Still waiting for some dev(s) to worldbuild a 3D game that blends "flat" 2D hand animated cartoon characters with lifelike 3D characters together seamlessly into a world/setting à la Who framed Roger rabbit.
 
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