Yea, I don't think it matter tbh, they'd just make some side game or spin off like we saw from Judgment if they even had one of the female characters have a title anyway
Like Reina's character (fun fact, she is voiced by Hiromi Tsuru the woman who voices Bulma in the DBZ series and Naomi in the MGS series., she passed away in 2017 R.I.P)
They could also do one on Haruka
or they can do one on a new character completely
They can go current times gangster Yakuza
or they can go Lady Snowblood Edo Period Yakuza or something lol
Because they've already done other games in this IP, they could just make it some side thing like we saw from Judgement or Kenzan, Ishin etc