doubtful.
Fans will simply buy both and they are just too different to even be compared. We don't know the era set for Ghost 2, it may have nothing to do with the last character and from what we know of the IP, its unlikely seeking some souls, Nioh type thing. Both titles simply take place in Japan......thats it.
Its like saying Yakuza Ishin will eat in sales of Ghost as if fans of that shit won't just buy both or something lol They'll be ok.
Roronoa Zoro
imho Onimusha 2 is the best one, followed by 1 and 3, 4. They are all great titles though regardless.