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Scientists Just Successfully Reversed Ageing in Lab Grown Human Cells

bitbydeath

Gold Member
This could end badly but it is fascinating.

We have been looking for ways to turn the splicing factors back on. In our new work, we showed that by treating old cells with a chemical that releases small amounts of hydrogen sulphide, we were able to increase levels of some splicing factors, and to rejuvenate old human cells.
Hydrogen sulphide is a molecule that is found naturally in our bodies and has been shown to improve several features of age-related disease in animals.
But it can be toxic in large amounts, so we needed to find a way to deliver it directly to the part of the cell where it is needed.
By using a "molecular postcode" we have been able to deliver the molecule directly to the mitochondria, the structures that produce energy in cells, where we think it acts, allowing us to use tiny doses, which are less likely to cause side effects.
We are hopeful that in using molecular tools such as this, we will be able to eventually remove senescent cells in living people, which may allow us to target multiple age-related diseases at once.

https://www.sciencealert.com/scientists-just-successfully-reversed-aging-of-human-cells-in-the-lab
 
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Maedre

Banned
In the end, there will be just a cure needed for the many diseases we call aging. I don't know if we will witness this moment where we will find a cure for most of those diseases, but it will happen.
 

Greedings

Member
They haven't done shit.

There's a mild recovery of genes associated with senescence. This is not "ageing" it's the inactivation of cells which leads to ageing in whole organisms. Studying ageing in cell culture is like trying to learn how to fish using an aquarium. Sure, you'll find something out, but it's not really important.

Remember, these cells aren't human cells, they're human cancer cells. These guys already grow like crazy. Their controls are also pretty weak, it's just low passage number - i.e. the number of times the cells have been grown on a different dish. This isn't really a relevant control for ageing.

This is an extremely over-the-top press release, from a rather boring paper.
 

God Enel

Member
I always have a feeling that you read stuff like that at least once a year for like 20 years and I'm still slowly dying
 
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