What are some examples of 2 main characters from a show that never crossed paths.

Recently I was thinking about how these 2 characters, Lunge and Johan's showdown happened in the anime Monster but when I looked it up they never actually came face to face. You would think before the story ends that they would have had some kind of scene together. I was convinced they had actually came face to face at least once.

What other examples are there of this you know of or even try and think of one and then go down the same rabbit hole I went down to find out.
 
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Unless it changed after I dropped off of the manga then Ichiro Miyata and Ippo Makunouchi in Hajime no Ippo

Some spars but no professional fight.
 
Saul and Gus Fring?
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Pls don't say but that was Jimmy.
 
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Raiden and Meryl in the Metal Gear Solid series never interact with each other a single time. In the final act of MGS4 they even both have cutscenes with Snake like one small area apart lol thats the closest they came.
 
Android 17 and Goku until Super.

Uh...Joel never crosses paths with Ellie and Dina's magic Asian child in The Last of Us. Funny, neither does Jesse. Sarah doesn't meet most of the cast because she got a shit roll on a check.

Palpatine had fuck all to do with Leia, Solo, and Lando.
 
Matt Saracen and Lyla Garrity never speak to each other in Friday Night Lights (or if they do it's incredibly brief--they have no meaningful interactions despite hanging out with the same people throughout their entire time on the show).
 
Well if movies and vilians count.

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Korben and Zorg never actually meets or are even aware of one another throughout the movie despite working against the other. There is just one brief scene where they are separated by a door and barely miss each other.
 
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Oh thought we were talking being physically in the same room instead of a zoom session.
JRR Tolkien truly ahead of the times. I suppose you could use it as an example but originally I kind of meant it in the literal sense of meeting one another. They've known about each other's existence for so long that you would think they'd have to meet for the story to have any kind of acceptable conclusion.

The Fifth Element one is actually a great example Kadve Kadve They did come so close to meeting as in literally on either side of a door but never did.
 
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