The lip sync and facial animations are just shockingly bad. Maybe that's cause I'm playing through The Witcher 3 expansion but and the facial animations and lip sync there are pretty great but holy shit this looks rough even by Bethesda standards. The over exaggerated body language doesn't help either. Like that salesman in the first video, the mouth isn't even close to matching up with anything he's saying.
The whole push towards BioWare style cutscene cinematics and the voiced protagonist approach seemed at complete odds with how Bethesda games have been presented before and at least based on these videos, that more cinematic approach just highlights how poor the animations and presentation is.
I was all ready to get this day 1 just because its Fallout but with so many other games out, these videos have really cooled me to the game. It looks astoundingly rough and janky, even for Bethesda standards. And not even in a goofy sort of way but just in a bad way since the shift towards a voiced PC and that presentation means somebody there thought what they were doing was good enough for that to hold up.