I recommend avoiding auto OC software. AI Suite installed some nasty low level hooks that caused my Windows 10 machine to take a really long time to shutdown. The only fix was to reinstall Windows 10.
It also took some messing around with custom batch files to actually allow the installation since Windows 10 doesn't allow you to run an installer that calls other executables. The tool also failed to set a stable overclock. It did an okay job until it started pushing BCLK. At that point, it failed to revert the BCLK and I had to resort a manual overclock anyways.
I had the SAME issue where Windows 10 wouldn't reboot. I managed to eliminate the issue by uninstalling that ASUS software.