In my church league, 12 team 1/2 pt ppr, qb, 2rb, 2wr, te, 2 flex, no kicker, drafting 2nd, I have:
QB: Deshaun Watson, Drew Brees
RB: Todd Gurley, Joe Mixon, Derrick Henry, Kerryon Johnson, CJ Anderson, Frank Gore
WR: TY Hilton, Juju Smith-Schuster, Jordy Nelson, Mike Williams, Dede Westbrook
TE: David Njoku, OJ Howard
D/ST: Chargers
I feel better about mid-round WR's than RB's this year, and with my league having 2 flex positions, I took 4 RBs early. Left me with a below-average WR group, and 2 guys with upside at TE rather than a sure thing, but I was still able to grab QBs I'm happy with - a ceiling and a floor.