Just finished the game and that last boss was really fun. I'm now trying to farm better weapons to try out TVHM, but I can't really find any good spots. Thinking back, I can't think of any bosses (other than the last one) that dish out any significant loot. Some of them can't even be repeated, and areas like the Eye of Helios (which I tried to go to for the Moonstone chest) aren't accessible anymore (I think).
It's weird, the more I think about it. The last game had Bunker, the last boss, the area with the Sheriff, and lots of others that were easy to get to and grind for loot. This one is the complete opposite. Everything is a journey to get to and even with the last boss I have to watch an unnecessary cutscene before every fight. Grinding is what this series is all about, it's strange that they would make so many design decisions against it. What would you guys recommend for post game grinding? I fought Meg tons of times and only really got skins. I can keep fighting the last boss until I can eventually get something cool. I don't know.