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Creating 'human-animals' for research

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ChrisReid

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Overall it's probably more general progress on the cloning genetics subject, but a couple lines are kind of chilling to see written in a CNN article. Realistically I think we have a great handle on the issue, but the field seems to be really booming right now.

http://www.cnn.com/2005/TECH/science/04/29/human.animal.mixing.ap/index.html

He can't wait to examine the effects of the human cells he had injected into the fetus' brain about two months ago.

"It's mice on a large scale," Chamberlain says with a shrug.

As strange as his work may sound, it falls firmly within the new ethics guidelines the influential National Academies issued this past week for stem cell research.

In fact, the Academies' report endorses research that co-mingles human and animal tissue as vital to ensuring that experimental drugs and new tissue replacement therapies are safe for people.


The National Academies -- private, nonprofit agencies chartered by Congress to provide public advice on science and technology -- consist of the National Academy of Sciences, the National Academy of Engineering, the Institute of Medicine and the National Research Council.

Doctors have transplanted pig valves into human hearts for years, and scientists have injected human cells into lab animals for even longer.

But the biological co-mingling of animal and human is now evolving into even more exotic and unsettling mixes of species, evoking the Greek myth of the monstrous chimera, which was part lion, part goat and part serpent.

In the past two years, scientists have created pigs with human blood, fused rabbit eggs with human DNA and injected human stem cells to make paralyzed mice walk.

Particularly worrisome to some scientists are the nightmare scenarios that could arise from the mixing of brain cells: What if a human mind somehow got trapped inside a sheep's head?


The "idea that human neuronal cells might participate in 'higher order' brain functions in a nonhuman animal, however unlikely that may be, raises concerns that need to be considered," the Academies report warned.

In January, an informal ethics committee at Stanford University endorsed a proposal to create mice with brains nearly completely made of human brain cells.

Stem cell scientist Irving Weissman said his experiment could provide unparalleled insight into how the human brain develops and how degenerative brain diseases like Parkinson's progress.

Stanford law professor Hank Greely, who chaired the ethics committee, said the board was satisfied that the size and shape of the mouse brain would prevent the human cells from creating any traits of humanity.
 
In the past two years, scientists have created pigs with human blood, fused rabbit eggs with human DNA and injected human stem cells to make paralyzed mice walk.

How do these mice get paralyzed? Do they make the mice ride little mini horses until it misses a jump? Also, do they have little wheelchairs for them? THIS is the real issue.
 

Pellham

Banned
anyone remember the story about the doctor who transplanted a baboon's heart into a girl? too bad she died...
 

FightyF

Banned
In the past two years, scientists have created pigs with human blood, fused rabbit eggs with human DNA and injected human stem cells to make paralyzed mice walk.

For some reason my mental picture of that was of mice walking upright on their 2 hind legs.

We were foolish to think that Stuart Little was CG.

Particularly worrisome to some scientists are the nightmare scenarios that could arise from the mixing of brain cells: What if a human mind somehow got trapped inside a sheep's head?

That'd make for a good movie. Terrorists put Osama bin Laden's DNA into a Koala, and it somehow gets into the US and it's mission is to assasinate the President. This koala can drive cars, talk like a human in broken english, and has all the CIA weapons training you can think of.

australie_koala.jpg


In the end the Koala dies of starvation because foolish Osama refuses to eat leaves, the very food that Koalas require to survive.
 
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