I worry not so much about friends of mine as I never truly had friends I could see being close for life. I do have 1 best friend that I've known my whole life and we will remain close forever. We are practically like brothers.
In terms of people that aren't in my life anymore, well, I come from a fairly large Italian family on both sides. Family "issues" arise and sometimes when people from the "outside" come in, it makes certain family members change.
For example, on my dads side (my dad is the eldest of 8 kids) he has 4 sisters and 3 brothers. Me and my 2 youngest brothers grew up very close with my dads side of the family. They aren't really all that much older than me (I'm 41 and my youngest aunty just turned 50). Anyway, for some reason the family has taken sides, and it appears like my dad is one "leader" and my dads 3rd eldest is the other "leader". And leader is probably not the right word but, my uncle doesn't talk to my dad anymore, so a few of the siblings decided to side with my uncle so they are on his team, whereas a few of the other siblings decided to side with my dad so they talk with us! It's so petty and childish. My dad hates it and wishes for peace but no matter how many time he tried to reach out to not only his brother but his other siblings, he gets the cold shoulder. In the end he has realized it's more important to focus on his kids and now grandkids than to worry about family who don't want a bar of him.
We used to frequent footy games with this uncle when myself and my middle brother were younger and now we don't speak at all. Sad state of affairs as we were all really close and now we have missed out on birthday parties and special occasions. My uncle's eldest daughter is getting married in November and none of are were invited. My brother got married a couple of years ago and he didn't invite any of them. It hurts but this is "family"...
And I honestly feel if people parked there fucking ego's this would all get solved but we have aunties of mine who hate my mother and aunties and uncle's who hate my dad. I'm sure they all have legit reasons in their minds but we are all adults and sitting down to talk should not be out of the question. Unfortunately there are some though that have gone too far and I will probably never speak to them again. Sad fact is, I have 4 kids that many of these family members have never met and never even reached out for. Hurt me and say shit to me all you want and I can move on but fuck with my kids, who are completely innocent and it is another ball game altogether. All it would've taken was a simple phone call when they were born and things would've been far better...