Definately a good book to read. Seriously, when you open it up it just makes your head zing, the humor of the writing... and its zingy cultural sensibility. Although, I found it a little uneven, because the parts of the novel with Alexis and his wonderfully maimed english and silly takes on American culture were so good that the parts going back to the sort of mythical past of Trachimbrod seemed too cartoonish, like sock puppet melodrama, and not on par with great Magical Realism a la Gabriel Garcia Marquez, Toni Morrison, Italo Calvino, nor with Foer's best parts in his own novel(which are, I don't know, maybe mildy...let me stress mildly..evokative of some of Barth's or Coover's stuff, or even Paul Auster..who is admittedly less the heavweight than Barth) etc.
Interestingly, when reading through czech author Milan Kundera's Unbearable Lightness of Being I noticed the words of Foer's book's title, Everything Is Illuminated, pop up in a sentence, though I'm not sure if that's where he got the title from.