I certainly know what you mean, but I got the impression that this emptiness was the point of it and actually made me feel a bit oppressed, especially in relation to my size and the oppressing nature of the color and sounds. Although to be fair, the game really seems to be more a tech demo/environmental showcase more than anything else and I can definitely see how it would probably alienate most people. Besides, I think its easier to get into "good looking" art experiences, rather than the oppressing ones.
Although I also lately thought about those artful games and how they might not appeal to everyone. I mean even the people who usually like these games (like you and I) might have issues with finding the spark among the more obscure games. For example I bought Proteus on release and I still wasnt able to appreciate it as much as most other people seem to be. That makes me a bit sad, but I guess some "artful" experiences just arent for me.
But that talk just made me think, I'd love to dig up a few art games and would love to see whether people react more strongly in favor of nice ones instead of the "oppressing" ones, even though their aim, evoking emotions, is basically the same.
Random aside: Try Kyoto. That is a very gorgeous art game.
Edit: Here is a video impression of the youtube Indie Impressions guy if you want to hear someone elses thoughts on Cesure:
http://www.youtube.com/watch?v=N3m_RiGhs3k&list=PL9Rlm-fZ2cj8zDA5rojJjDdmjFQGUFu7W