Personally i have stopped reading/watching manga/anime a long time ago but there are some that i really love and i think some have the potential to become interesting games. One such manga is Blame! by Tsotomu Nihei.
Blame! often comes up in many people's wishlists when we are talking about what type of a potential FromSoftware sci-fi Souls game could be or what type of a sci-fi game people would love to see. I think the manga has a very unique setting and story and i think it has the potential to become a great game in the hands of the right developers.
Interestingly there is already a game out there that draws a lot of inspiration from Blame! and that is the indie game
Memory of a Broken Dimension.
But although MOABD is amazing (especially when considering it's the work of one man) i was thinking more of a big budget game that directly brings Blame! to video game format but also has something of the aesthetics of MOABD. Two developers that would have been great for a Blame! adaptation are FromSoftware and Ueda's GenDesign IMO.
So what manga/anime do YOU think has good potential to become interesting games and if so from which developer(s)?