So it turns out the Heavenly Island manga is not actually a prequel to Revelations 2 as implied. It's set in 2014 as a prequel to Umbrella Corps while also answering leftover plot threads from BIO5 and REV2.
In particular, the setting is the island mentioned in the Lost In Nightmares file
Spencer's Memoirs 2. Claire calls Chris for support, but he's busy on a mission in the U.S. and instead recommends Parker Luciani. Claire also discovers a photo of Alex Wesker and an unknown associate who brought B.O.W.'s back to the island.
This also explains why TerraSave now have GPS trackers in the manga but didn't in REV2. The kidnapping spurred them to include it on each member's phone.
The manga is great. Very surprising considering the initial setup is gratuitous sexuality, but it functions more as a way to throw the reader off. The suspense and mystery are great. It's a vast improvement over the yawnathon that was the Marhawa Desire manga. There's still a lot for the manga to answer but the story is one of the more compelling to come out of the series in over a decade.
There's a new pharmaceutical company
Shényā Pharmaceutical based in China that is trying to recover Umbrella's research results on the island and resume a "project." By recording footage of a certain B.O.W. on the island massacring celebrity idols and broadcasting it globally, the company also hopes to renew interest in B.O.W.'s among dictators and terrorists. An agent of this company could be mistaken for HUNK at first glance, but the outfit they wear actually looks like the soldiers in Umbrella Corps.