As far as Orochi is concerned? I think that Orochi should get a rest for a while after this MO2 update. I need to see what they'll do for Sengoku Musou 4 first, and again, it really needs to be something special after waiting so long, and with Sengoku BASARA 4 releasing at or around the same time.
Anyway, as long as the Musou style shows no signs of stopping? I'm all for more brands getting adapted to it. If Sophitia's appearance in the MO2 update isn't at all a sign that Bamco is getting them to make a Soulcalibur Musou spin off (re: "Lost Swords"?) I'd be surprised. They'll need a quick and easy way to reel fans back in along with SC2HD, while Project Soul works on the definitive next-gen sequel.
I don't think Namco is too keen on revisiting a Musou-style game for the Soul Calibur franchise again.
...Unless they just handed the IP to Omega Force and said "do whatever you want with it" anyway.