The story completely falls apart under any scrutiny. Example. It's established right at the start that the rain causes accelerated aging if it hits your skin.
Then we see our main character in an open faced raincoat riding a motorcycle in the rain. It's baffling that he wouldn't be wearing some kind of face covering, especially on a bike, where his forward velocity will absolutely cause rain to hit his face.
So why is he not wearing a mask? Because it's important to the director that we see that Norman Reedus is in the game with full motion capture. Story and universe context be damned.
Okay. Next we have a city, somehow the city is immune to the rain, they have figured out some way to keep the city safe. But, bafflingly, they did not extend that protection along a road to the incinerator. I mean this is a society where any dead body turns into an antimatter bomb, but every delivery to the incinerator is essentially a dice role of chaos and risk? Is it any wonder the entire city is destroyed… something the game mentions briefly in a side comment from del toro, with no weight given to the massive loss of life that just occurred.
I get this is all a nitpick. But it was clear to me that this game is all about vibes, celebrity, and pretentious writing.. it's not nearly as well thought out as it gets credit for, and it's a painfully boring game to play (at least in the few hours I could stand playing)