Pretty much. When Jeff jokes about hating Yoshi, it's supposed to be funny and you get the impression that he doesn't really care. When Dan says he hates something, you assume he's serious.
I mean, I've been mostly staying out of the GB thread because it's not really the place to raise a stink and if people like him, that's fine. But I still listen to the Bombcast and stuff like his Monster Hunter rant is just unavoidable for me.
I think it's all tone. When the Red Letter Media guys spend 30 minutes tearing apart The Order 1886 and then light the game on fire on a bed of matches that spell out "FUCK YOU", it's informative, critical, and funny.
All I got out of the MH segment is Dan pretty much implying that people who may enjoy the games (and let me be clear that I don't have an opinion either way on MH) are completely misguided and that the games are objectively terrible.
Whether or not he means that, I don't know. But that's the impression I get when I listened to that segment.