The ground swell for a qualified female president, when all is said and done, will completely overrun whoever her opponent happens to be. Women in this country, as well as many men, want this to happen. Many will also see electing Hillary as the surest way possible to protect President Obama's agenda as well as all the progress that has been made during his two terms as President.
Maybe it's a bit much to say she's guaranteed to win, but she's the heavy favorite to win, and for damn good reason. There isn't another Barack Obama showing up to stop her in this election cycle, not on the Democratic side (although I do love Bernie Sanders), and for damn sure not on the Republican side.