My predictions, trying to keep this all fairly realistic:
- Starts with a God of War IV gameplay demo. Kratos in Norse Mythology messing stuff up with massive axes and hammers, ending on a scene as he's riding Fenrir as Thor casts down lightning bolts at him.
- Dead Don't Ride from Sony Bend. It's Dead Rising x Mad Max, with motorcycles. A dumb fun over-the-top open world post apocalypse action adventure.
- A cinematic trailer for Detroit: Become Human. More androids-want-to-be-human melodrama with good acting but bad dialogue.
- A sizzle reel for some big already-released 2016 games, maybe with some kind of 'The best place to play' tagline: Dark Souls 3, Uncharted 4, Overwatch, Alienation, Battlefront, Doom (if Sony have the marketing?), etc.
- Another sizzle reel for upcoming exclusives: Gran Turismo 6, Ni No Kuni 2, The Tomorrow Children, What Remains of Edith Finch, Wattam and Persona 5.
- Maybe a trailer for Uncharted 4, along with a bunch of awards and acclaim it has gotten. I think it's going to be too soon for any story DLC, although we may see some new multiplayer maps. They may announce it has sold X copies (4 million?) and thank the fans for the journey.
- A gameplay demo/trailer for Dreams, possibly with a release date, and definitely a beta announcement.
- A cinematic trailer for Nioh. Visuals looking considerably improved, and it shows an emphasis on boss battles. Dated for Q1 2017.
- Gravity Rush 2 shows up with a brief hyperactive trailer showing Kat adventuring and taking out bad guys with her powers. Looking beautiful and better than ever, and the trailer ends with a release date for October 2016.
- A sizzle reel of upcoming PSVR games - RIGS, Driveclub VR, Until Dawn: Rush of Blood, EVE Valkyrie, Robinson: The Journey, and so on.
- Hopefully followed by a look at the final PSVR hardware and release date.
- PS4K next. Uncharted 4 will be the first game to benefit from the hardware boost, upping the campaign to 60fps. All first party hardware will take advantage of this with games having increased performance on the 4K, but none will be exclusive to it so all software will still be available on regular PS4. Releasing alongside PSVR later this year for $399.
- Horizon: Zero Dawn. New gameplay trailer showcasing the open world, variety of environments including towns, ruined cities and mountains, gameplay systems like accepting missions and trading, and more of the combat.
- Sucker Punch will debut their new game - I'm expecting it to be a new Infamous, probably with Delsin again. Hopefully the mission design will be better in this and the city will feel more alive.
- Probably some COD: Infinite Warfare and Destiny: Rise of Iron stuff. Hopefully Destiny continues to evolve; with missions and storytelling resembling The Taken King. Infinite Warfare will silence a lot of critics as the gameplay will actually look very solid and the spacefaring combat a lot of fun.
- The Last Guardian shows up with another few minutes of gameplay. Visually looks similar to last year but looks just as charming as ever and it ends with 'September 20th 2016'.
- Finally, we end with a gameplay trailer for Crash Bandicoot Reborn. Starts with him running down a corridor similar to the PS1 games (may begin with the PS1 visuals and fade into the PS4 version), and when Crash reaches the end of the corridor it opens up into a large level showing a jungle, wide open areas and, in the distance some kind of ominous tower or building, and as the picture fades and the camera pans back we hear Cortex' laugh. I'm thinking a semi-open design like the original Jak & Daxter. Made by Sanzaru Games.
I'd really like to see a new game from Japan Studio as well, but I think that will be held back for TGS or PSX.
EDIT - I might have forgotten a couple of obvious ones, and some of these (like Detroit) might be held back for other shows.