I think we'll see TLoU 2 at the presser, but it won't be anything fancy. Another short scene focused on character interactions maybe. Our first glimpse at an (even) older Joel would be a good bet.
I agree with Drifting though, Sony don't really need to show it and I don't think there's much pressure on them to do so. They're holding so many cards right now that they can play any matter of different hands and still deliver a satisfying conference. If TLoU gets ignored, but we're still shown the likes of GoW, Spider-Man, Death Stranding, FFVII, Kingdom Hearts 3 and Gran Turismo, then most people aren't going to begrudge them for a lack of naughty dogs.
Please come out of your hidey-hole and make a big splash at E3 Dreams, pleeeeease.