I'm not sure why the default settings of a game don't hold? That's how the developers intend you to play it. Is turning off the quest markers as detrimental to the experience as say, Skyrim? No. But the quest design does fall back on the waypoint system. It's a losing battle, but I really want open world games to return to the likes of Morrowind. No maps, just in game quest dialog/text and sign posts and with a limited fast travel system (Silt Striders) that made since in the game world. I use this as an example a lot, but one of my favorite quests in Morrowind's original PC release gave you incorrect directions. I'm not sure if it was intentional or not (knowing Bethesda, probably just a QA error) but those bogus directions while frustrating, lead me on a whole other adventure. And speaking of Breath of the Wild, one of my favorite side quests in that game just gave the player somewhat cryptic directions to a hidden chest. Personally, the exploration in the Souls games is far more rewarding than anything found in the Witcher.
Witcher 3 just follows modern open world design philosophies of leading players by the nose to every piece of content with the fallacy being that these games are so jammed full of content that most players aren't even going to finish the game, let alone track down every side quest. Like I mentioned before, it's a lack of confidence in your game design, much lack the Batman Witcher visions that highlights environment clues when tracking.
I didn't say it wasn't an RPG. I just don't think the RPG elements are anything special outside of the dialog choices. The character build choices feel largely inconsequential and that has a lot to do with how rote the combat is. And that's why I draw the Assassin's Creed/Batman comparisons, for the combat systems, not necessarily the open world design. I probably put in as much time with AC:Origins as I did Witcher 3 and I can tell you exactly the same information about both experiences which is hardly anything, as by in large, they are mostly forgettable. That's not saying either are bad, they are just easily flushed from the memory banks. And to be fair, Bloodborne's implementation of traditional Souls style character building is pretty bare bones. The only reason to start over with a fresh character in the game is to gain access to the rarest crafting materials to max out the various weapons. But I can still recall every nook and cranny of that world, every enemy encounter and every boss fight.
So what is memorable about the Witcher 3? To me, that is the dialog, characters and story so I don't see the TellTale comparison as a knock per se. I'd replay the hell out of the Witcher 3 if presented like The Walking Dead just to see the different narrative outcomes.
Maybe this is all "poor form" or maybe you take insult where there is none intended but I wouldn't count my chickens before they are hatched. I do bet you love Twilight though.