well Ryan did say what he wanted to do with Halo 4 was a big departure from the norm and it seemed like the rest of 343i didn't have the same idea. Now we know covenant/unsc/halo 1 vehicles are in it so I did almost immediately think of Payton when i saw those
I still hope for a more fresh take on the series by 343 but the UNSC/Covenant vehicles were somewhat of a bummer...the new trilogy should've been a new start for the series (at least for the Campaign, MP is another story) and as stated numerous times by a lot of folks here Metroid Prime could've been a great source for influence.
The Halo series is amazing, I've played and loved all the games spending a lot of time in the campaigns playing solo & co-op and Firefight in Reach and ODST but the series needs to change to keep things fresh and exciting and I'd go as far as to say that I'm all for it if that even means no co-op in Campaign if the game needs it for example.
I really hope 343 will prove me wrong when we'll actually see the game (hopefully way before E3...right Frankie?) but I'm not holding my breath...sadly as the time passes by things seem to settle as far as what our expectations should be in terms of risk and originality for the game and I find the wishful Metroid Prime-influenced scenarios more and more unlikely.