Rogers was not the first to be given the Super Soldier formula. It was revealed years later that while Rogers was still being assessed, some military members of the project felt that a non-soldier was not the right candidate and secretly gave Erskine's incomplete formula to Clinton McIntyre instead. However, this made McIntyre violently insane, and he had to be subdued and placed in cold storage. The criminal organization AIM would later revive McIntyre as the homicidal Protocide. (Captain America Annual, 2000).
A beta version of the formula was given to Isaiah Bradley, who became the only survivor of a group of African-American soldiers that "Reinstein" and the military experimented on in 1942. After the last two members of his group were killed, Bradley stole the costume meant for Rogers and wore it on a suicide mission to destroy the Nazi super-soldier effort at a German concentration camp. Bradley was captured, but eventually rescued and court martialled. He was imprisoned for 17 years in Leavenworth until he was pardoned by President Eisenhower. By the time of his release, the long-term effects of the formula turned Bradley into a hulking, sterile giant with the mentality of a 7-year-old. Rogers would not find out about Bradley until decades later (Truth: Red, White and Black, 2003). Patriot, leader of the Young Avengers, has been revealed to be the grandson of Isaiah Bradley.