One of the biggest entertainment franchises in the world with an immense amount of hype, 12 years of development with 6 years of intensive development, cost probably in excess of $2.5B by now and well over 2000 devs working on it.
I think they have to deliver or it'll be a shitstorm of disappointment.
Not to mention the morale of this whole industry seems to be resting on this game as a saviour; and Take-Two is horribly managed with the entire company pretty much counting on them.
We're still waiting on truly next gen experiences 4yrs into this gen and if they can't come up with something that feels fresh and raises the bar, I think the whole AA+ to AAAA space is buggered. If R* can't push the limits then no one else is gonna bother.
Also, this dev left R* just after GTA IV came out..