I was quite disappointed with the game, because of several reasons.
1. The game is a slog during the first chapters. The first third of the game is so slow, that I will never want to replay the game.
2. The areas that opened up for gamers offered absolutely nothing for those who don't care about collectibles. "Lets create these more opened up areas because fans wanted it, but lets not include anything meaningful except pointless collectibles related to trophies". Don't care about collectibles? You are out of luck, because you will find nothing off the beaten path.
3. These so called opened up areas during the shooting parts weren't really that much bigger than the ones in Uncharted 1-3. I expected bigger areas to fight in, especially after seeing the E3 demo and Naughty Dogs going on and on about the game having bigger areas. It was mostly either path A or B.
4. Story was good, but predictable. I can't believe more people don't call out the game for this. The twists were more predictable than an average horror movie. And please, for the love of God, don't have Oscar worthy and Uncharted in the same sentence (I just did though, lol). I can already feel the puke halfway up my throat just by thinking of it. Oh and lets shoehorn in a brother and make a story around it because why not.
5. The game really should've had a crafting system ala Tomb Raider or The Last of Us, or at least an upgrade system. So that they could've actually filled those open areas with something meaningful.
6. This is a minor one, but there were so many times where you got put into a "sitting ducks" situation when it comes to the shooting parts. This was especially frustrating in Hard mode, where only a couple of bullets would kill you. Why did the developers this? I'm going to tell you why. They wanted to force you to use their new, game changing and revolutionary rope swinging mechanic. And yes, that's what they indicated that it was, even though people have been swinging ropes since Pitfall. The developers wanted you to desperately use said ropes, but this was almost impossible on Hard mode, and made for a lot of trial and error. Again, rope swinging mechanic and revolutionary in the same sentence, the puke has already ventured through my throat and is on its way out.
7. Predictability in gameplay. This is also a minor one. But shooting parts followed by climbing parts, became a pattern way to often with a couple of puzzles thrown in.