Monster Hunter needs a usability revamp and a home console release if it's going to sell gangbusters in the US.
If they're tied to Nintendo, I don't know that they can go but so high, regardless of the quality of the game (MH4U is really good).
Curious to see what they do with MH5 for sure. They did a lot of work making MH4 more accessible, but it still has a lot of stupidly arcane systems (and that's above and beyond its inherent basic barrier of entry due to controls, challenge, game structure, etc).
The dream would be a multiplatform release, but it may be that they're both tied to Nintendo, and perfectly content to focus on handhelds first with the series... which seems really strange, but who knows. Financials must make sense for them.
All that aside, glad it did well, and glad it's getting a warm welcome here, MH is one of the absolute best game series out there, and not nearly enough people have played it.