Here is a pretty good checklist if you're doing a speedrun.
MANSION (First Visit)
- Find Kenneth
- Return to MAIN HALL
- Get ARROW; examine for ARROWHEAD
- Use ARROWHEAD in GRAVEYARD
- Get SWORD KEY
- Get WHISTLE and LIGHTER in LIBRARY
- CHRIS ONLY: Get OLD KEY 1 from SAVE ROOM
- CHRIS ONLY: Get OLD KEY 2 in BATHROOM
- Get CHEMICAL (using OLD KEY 2 if playing as Chris)
- CHRIS ONLY: Get OLD KEY 3 in KITCHEN
- Get BROKEN SHOTGUN (using OLD KEY 3 if playing as Chris)
- Get SHOTGUN in SHOTGUN ROOM using BROKEN SHOTGUN
- Use DOG WHISTLE in TERRACE (using OLD KEY 1 if playing as Chris); get IMITATION KEY
- Get ARMOR KEY using IMITIATION KEY
- Use CHEMICAL in PLANT ROOM; get DEATH MASK 1
Get GRENADE LAUNCHER from TERRACE (ignore HERBS)
- Pass Richard to the DARK ROOM (retrieve SERUM from MEDICAL ROOM to save him if playing as Chris; optional if playing as Jill); get MUSIC NOTES
- Get CREST
- Combine MUSIC and MUSIC NOTES; replace GOLD CREST with CREST
- Get SHIELD KEY using GOLD CREST
- Get DEATH MASK 2 in SNAKE ROOM
- CHRIS ONLY: Get OLD KEY 4 from KEEPER'S BEDROOM
- Get DEATH MASK 3 in ARMORY
- Get DEATH MASK 4 in PICTURE ROOM (unlock gate to GRAVEYARD using OLD KEY 4 if playing as Chris)
- Defeat CRIMSON HEAD ELDER; get STONE AND METAL OBJECT 1
Residence
- Stop the red windvane at WEST and the blue windvane at NORTH
- Get CRANK in CABIN
- Use CRANK to get to GUARD HOUSE
- Get RED BOOK
- Get ROOM 001 KEY
- Get CONTROL ROOM KEY in ROOM 001
- Enter CONTROL ROOM in AQUA RING
- Press the buttons in the following order: DRAINAGE, SAFETY LOCK, SHUTTERS, OIL PRESSURE, SAFETY, SHUTTERS, DRAINAGE
- Defeat MOTHER NEPTUNE; get ASSAULT SHOTGUN and RESIDENCE KEY
- Enter WASP HALL using RESIDENCE KEY; get INSECTICIDE
- Use INSECTICIDE on WASP NEST; get ROOM 003 KEY
- Get WHITE BOOK; solve book spine puzzle
- Defeat PLANT 42 using FLAME ROUNDS as Jill or ASSAULT SHOTGUN as Chris (if Richard was not saved with the SERUM, time will be wasted creating the V-Jolt if playing as Chris); get HELMET KEY
Mansion (Second Visit)
- Get JEWELLERY BOX in ART GALLERY
- Get RED GEM
- Use RED GEM on JEWELLERY BOX for BROACH; examine for EMBLEM KEY
- Defeat YAWN in LIBRARY; examine BLUE BOOK for MEDAL OF EAGLE
- Get METAL OBJECT from SPENCER OFFICE
- CHRIS ONLY (Optional) : Save Rebecca by going to the LIBRARY (room where DOG WHISTLE was found)
- Get RED BOOK in STATUE ROOM; examine for MEDAL OF WOLF
- Follow path to KITCHEN; use elevator
- Get BATTERY
- Use BATTERY on broken elevator in COURTYARD <use SQUARE CRANK at the bridge to drain water>
The Catacombs
- Get HEXAGONAL CRANK from Enrico
- Skip BLACK TIGER fight
- Get CYLINDER
- Combine CYLINDER and SHAFT; use code 4231
- Use ELEVATOR
- Enter LISA CORRIDORS; send off the BOX
- Return to ELEVATOR ROOM and get BROKEN FLAMETHROWER
- Use BROKEN FLAMETHROWER to unlock door
- Get STONE OBJECT from JEWELLERY BOX; combine with METAL OBJECT to get STONE AND METAL OBJECT 2
- Get STONE AND METAL OBJECT 1 from COURTYARD; use both to enter ALTAR
ALTAR and UNDERGROUND LABORATORY
-Let Barry die to get BARRY'S MAGNUM
- Use MEDAL OF EAGLE and MEDAL OF WOLF to enter UNDERGROUND LABORATORY
- Go to COMPUTER ROOM to unlock floors; username: JOHN, password: ADA, 2-F password: CELL
- Get LABORATORY KEY in PRESENTATION ROOM <use code 8462 on the keypad>
- Get FUEL CAPSULE in POWER ROOM
- Charge FUEL CAPSULE and return it to POWER ROOM
- Enter POWER ROOM 3 and switch on the power
- Use ELEVATOR; kill TYRANT with BARRY'S MAGNUM
- Get MASTER KEY from Wesker
- Return to UNDERGROUND LABORATORY ENTRANCE and use MASTER KEY
- Get FUSE UNIT and use on ELEVATOR
- Get SIGNAL ROCKETS and use them immediately
END
