I haven't had much problem with CWS....
Now, those damn spyware that install proxies and screw up TCP/IP communication... THAT pisses me off.
I've got a process down now that can neutralize any spyware though.
Boot to windows and unplug network cable or disable the nic
Boot to ERD Commander (most people are not going to have this) if you don't, you can try booting into safe mode (but the spyware processes may still load which means you can't remove them manually--thankfully Giant AntiSpyware can somehow kill running processes--even the ones that normally don't end when you try to kill yourself through the task manager)
Manually delete registry keys, program file directories and any unknown services in the control panel
Boot to windows normally and run your spyware tools (I use Giant AntiSpyware, CWShredder and HijackThis)
Make sure no spyware process are running and re-enable the nic
Problem solved