I dunno about Apocalypse. It is coming off the most successful X-Men team film (I had to add the team modifier because of Deadpool), and was one of the most well received entries in the series and comic films of the last several years.
Add in the addition of a recognizable bad guy for most people (even if Apocalypse sucks), and the same creative team as DoFP, and it has just about everything going for it.
I think it will set the opening weekend record for an X-Team film at least. After that, it is all about how well the film turns out. I think the opening weekend will be big because of the goodwill that DoFP gave them.
Shit, I am ready for Singer to do whatever he wants after finally giving me a worthy sequel to X2 after more than a decade.