It also should be interesting to see how my impressions are compared to my girlfriends. I've watched all the Marvel movies leading up to this one, while see hasn't seen any. But she is still extremely excited to see the Avengers next Saturday. I just hope I don't have to do a ton of explaining throughout the movie lol.
I saw it with my wife, who has seen practically all the Marvel movies with me (except for the first Iron Man, which was before we met). She's not at all a comic fan/geek (although she loved the 1st Iron Man movie; and Thor and Captain America for the leads) but she was laughing and clapping along with the rest of us. This movie is something special. You guys are going to love it.
Honestly, I haven't been this excited post a superhero movie since TDK. Not in the same league, mind you, but they are both great experiences.