In regards to Rift disorientation, I've found it helps to have something to focus on outside the ship. For example, if you're just staring off into space, you get all loopy when you move, but if you're following another ship in a dogfight, and keeping your eyes on him, you can twist and flip the ship in every damn direction and it feels fine.
I tend to do better in open space, getting near the stations gives my brain something to reference, and the disorientation gets worse (like when I'm docking).
Same, I can get a bit disoriented from time to time. Like for example, I can stay outside of station and be completely stationary, but the movement of the station will give me headaches from time to time.