Spine has a dozen different export formats. If your engine doesn't support the default JSON and atlas files, you can export a GIF of PNG strip or whatever.
I may be overestimating the significance of my particular Photoshop animating quirks and nuances, but I always felt as though starting to add Spine produced units into the game would cause some some visual dissonance. I could be wrong. Maybe I'm wrong. I'm probably wrong. Maybe I should do more Spine experiments.