While conducting an interview on 4gamer for their new upcoming RPG Frontier Gate a couple Konami employees stated that they were designing Frontier Gate from scratch as they had previously disbanded their Suikoden team and had therefore lost all their RPG-creation know-how.
Needless to say this is grim news for the Suikoden community. But, it does not mean a new team cannot take over the Suikoden name later. Konami has done this before with other franchises, such as Silent Hill. There is also still the possibility of re-releases of existing content and side projects, such as the Pachislot machine.
//Mod Edit:
The person who directed Suikoden Tierkreis is working on Frontier Gate, so that means it's quite unlikely that Konami is working on any kind of Suikoden project for the foreseeable future.
Frontier Gate is also a concept that came from Konami itself, and seems to be their only internally driven ambition in the RPG market right now, as Labyrinth was an idea that spawned from Tri-Ace. It was a bit like a trade, where Konami would publish Labyrinth (Tri-Ace's idea) and Tri-Ace would develop Frontier Gate (Konami's idea).