I have a recording of one of his recent concerts (not the Sac one) and not maybe 10 minutes into his set, the "WHAT!" and "I'm Rick James BITCH!" quotes came out and didn't stop. He cracked on them, but they were relentless.
Basically anytime he was trying to transition into another joke and there was a pause in the routine, someone would shout something out.
He didn't snap, but he said:
"When I started, audiences use to actually, like, listen to the show. Then, it was around when MTV half hour comedy hour started, this whole thing came out where the audiences would be like 'WOOOOOOOOOOO!' 'OWWWWWWWWWW!" Which is good, if you're a rock musician."
"...these guys think they're helping me out. They think that I'll come here and don't know what I'm gonna do, like 'Man, I hope somebody in the audience screams some shit out to give me ideas."
"Not to say I don't appreciate your enthusiasm, but I'm just being real. Its fuckin...annoying."
I can fully understand the situation. Of course a comic is supposed to run with it, but within a week of the Rick James skit, I was already tired of corny ass dudes saying it, and it was ran into the ground. Imagine how many times he hears it in his daily life, and then when he's trying new material out, people try to take over your show.
He said during the routine that he wasn't going to quit, but he was sick of it.
BTW, his set was fucking hilarious.