I think if AdBlock really is that big an issue for Content Creators, they need to be extremely careful with the type of ads they allow on their content. Ad creators are the ones who pushed everyone into using Pop Up blockers, AdBlock, NoScript, etc. because of not only quality of use problems with the ads taking over focus and auto playing as loud as possible noise, but also for security reasons.
I don't think it is very fair to ask users to put their systems at risk.