I have a profile, the trick works with DSR though.
You do need to use a console command in-game to comfortably downsample:
Pillars of Eternity downsampling guide:
To get the best image quality on the 3D rendered stuff, while maintaining the full quality of the backgrounds, I suggest this (if your hw can handle it):
- Downsample from exactly 4x the resolution (e.g. I'm using 5120x2880 on my 1440p screen).
- Since this is a Unity game, if you are using DSR you will need to set your desktop resolution to your downsampling resolution before launching PoE for this to actually work. (It just works with GeDoSaTo)
- UI will scale automatically, so there's no need to do anything regarding that.
- Your zoom limits will be messed up though: by default the game won't let you zoom closer than a 1:1 mapping of background pixels to display pixels. Since you are downsampling, every "display pixel" the game sees is actually just 1/4 of a physical pixel, so you'd like to zoom in further.
Luckily, this is easy to fix: open the console (look up the key for that in the options) and type "setZoomRange 0.5 100". 0.5 will let you zoom in such that you get 1:1 mapping of background image pixels to real physical pixels again with 4x dowsampling.
- Additionally, you can use the command "msaa N" to enable NxMSAA, e.g. "msaa 4". It doesn't make a huge difference on top of 4x downsampling though.
Edit:
just noticed that this is already in the OP.