I personally think that as long as we continue on the path of fuel/propulsion, space travel will never advance. Unless I suppose propulsion could be though of in abstract ways. It sounds hokey, but I believe the only real logical explanation or way to advance in space exploration is through our understanding and eventual manipulation of time.? (this is both a statement and a question, because I have no idea what I am talking about)
Edit: I have no delusions or doubt, we are not alone. Perhaps though we have already encountered life, but it is totally unrecognizable, or indistinguishable to our limited thinking or comprehension.