Just want to chime in with some thoughts, since the first became my favorite platformer ever(I beat it all six times, and with Asagi, and killed all the uber bosses shy of Baal and Lil' Asagi[though I cleared her stage]).
-The voice acting is a train wreck. So is the localization. Even the best boss from Prinny 1, Darth Moab, has soulless, dull dialogue. It's like they weren't even trying. The only saving grace was Joshua. Her voice and dialogue was great.
-The game is so, so much harder. Mostly cheap hard, but the sense of accomplishment is still there. The stages are creative, and lots of neat new enemies, including some D3 arrivals.
-The final boss is insane, and a totally different kind than Sir MFin Sweet.
-The Pram stage is on PSN now, and is free. I'm afraid to try it. I'll have to kill the final boss first, and that may take a miracle. (I'm at 502 lives now.)